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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a894fdff383f5e54be2922dc0a18d1055a89d4de74e434ddfc4a76959f12144' 
  AND token = 'rndMhjYPbBfvAJbnEStsZOw9aM+y0c4I0Kg83MiuRzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}