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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6281e374012d0e7a7cfb27e731e33ddcd5e00b8b9378d475dd23f7f87d4c08' 
  AND token = 'KY8zSY8LNKibC3LBoyTkReeuSxe4Mh2PyLSCuqTqfpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}