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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80382e99fef3edc6ee1a8895ab9c4557dd61341063913c19695168253ff0c6f' 
  AND token = 'xes8hy1SxBGr/JkKAtp30PbvgzwhPRs7M6STbCC4/xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}