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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22929a32fc8d59994c214f4e08e7e464e11c75b55f7615fc9988869990cd53ad' 
  AND token = 'gk+j3EpydW2vQHG9OCaNNgQAIHZC6GcyKKfdcmbLq1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}