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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e4d9233d406d7987595e485054446775d341e5455d6d813332cba1a94bd510' 
  AND token = '+Ef1PbNuxAgxXOTVRV6sEjPe6wwSV3OEq8G2+rCjKlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}