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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a24d103cdf4ae02f4c2c8917de5fbe0200c0b12be3746aa4f821621d3d78ed18' 
  AND token = 'T1CIB0FbYSPBAlPJS6kSF4GXEKaMnL5BYZZXd9daBpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}