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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39310fd11afadc43e7959adf0b1c6928fc9c0c8a7057e281954bef7d8e9b21b8' 
  AND token = 'iTK8vpBi3k2Ug5vv7iW5vte5eYDlhZiqAY/mzm+RvOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}