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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb6cd487c03a8d8be4815df79f3fcc42d69720b3e3876d463603ebaa6a4ce62' 
  AND token = 'p+asNV1qnfvAwHYPE+5h50OM/qhws2cuxQ+OyFw57MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}