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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3a2ffe129b4c6d4e2e579ba65565ef449b3629531edd8b4e17b207b7909f13' 
  AND token = 'uPPrSYw//Knl42/b38ofI6UamO2whia1X+50N//z5gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}