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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e073b685b937afd15ea01836ce519077e28d411b4778f3d61a4ad9eeb3346180' 
  AND token = 'Nmsw1NobTUkzrjp6bT1alZGg08jveyCogMveDrRuVFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}