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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60345711adebada85ec7f92e80a86278f2c9eacdf12ffe3e6f4dd4a434fc2236' 
  AND token = 'uO2NUCa0NlXPrKhMtH8q5hZvgiSnXKQPJlpE6vBQSy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}