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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '509d82afdb5a31f0a7c5692c6ada7b2435c4e794db6c25c99cc8f8aed6ffb588' 
  AND token = 'uqBExyOanvHODDyutXIYyePFSHS0mJJbYRdoDz7zlfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}