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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb23491623a4883089f9f5dcb1a9acd45cd79d38b4947b49888c28048008e8d' 
  AND token = 'GROfnVSgsGGsQIv1Q6KnNTb6rQUbqoV5T1ax4NKWNW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}