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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dbec75a46e00978acb6e1233ad59885f11bc1f53ef782e04e1040e50e0ab8b' 
  AND token = 'ZtDzCOHXtxCB9sjt9th/ti6Fp7PzGrYtkT0VGFWtDWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}