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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d01f4d3d09c5e2f7ddcf8a58ad2e0fba58d789cfabd11b66547bbf0965622d2' 
  AND token = 'Lv0hH1yMqTIMqRqxBJV+yfeet8AWNQySiQw/+w25XUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}