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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1020c0f68c95eb90faa80c429f70776841c6bb9295497ffb2b8cc391f015229' 
  AND token = 'ARFajk5Elw+aaaHkUeLF2jtZtiBEA9VGuvAWQ/tYIlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}