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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c80ead6e809ea0cd67f51ecbaf3231d3819bec6bffa32f8c8db664701e8831' 
  AND token = 'nl0koV7WBsnmcdhbyRsJ76DRvzEDIhxOlSa4NmN0s0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}