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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f5de264654c216bbebdd92521631bdff6cf0a6a7eb6936a96064c856439566a' 
  AND token = 'V++vzyk22srBw44zX3qEFyuy1I0IAHcK9OZzYAhYy3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}