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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18467eb19dc1fa0593348cf183aba111cf4125dc429d11fb96009756f7d38528' 
  AND token = 'on19KkhjPC4eprWf/gxBExiXO/gKUTMO9qlkbCO8ahQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}