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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de60ea0e134874e344b83a3510e85d57f33fcdeeb16fa5a822cd731a0dab517' 
  AND token = 'cK4Jt5F5QZVsWgo02c+eel8k7oF/rv+CFMh4qIFpbPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}