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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '568f7a1de32dea372ae2bb7d9a5036d2e7e1b5be321962bd8d94bce7acc65338' 
  AND token = 'w9kFBGqL5rbC3VjAum77/Fw0VSXaGsKnfmkS0OKAhzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}