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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8eda40d5079286b665aed90ac56c1ab94e3e583dbf53077bf9eb60777be7016' 
  AND token = 'niVfTx2jG6G+4lokmfvDWhnnppJJKUj5eSiOn1D2Au0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}