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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f9409c5607011da658581efdcc9541cda7a78ca02291f0f0ef23c59978ed73' 
  AND token = 'X3p2su6UGy3UD8AM2Nh3AMjErKd5Rg8R67cVhUvGhns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}