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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef93f40d184aa69e2817144a7c02d375fda6f719d1d03f948e6ba00b9cf0405c' 
  AND token = 'eAVvGim4K2/eSdNsvY2Q0wSqLgZ/CfFft7Wu7Msnibw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}