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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910b5014ee8be4e4dbb878372752d18259af25a1179baccb32f77c1f72ce008c' 
  AND token = 'emNKOWFuLDm5SGQWJ7/M+mb11pY3nH5AjvkFffmPbvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}