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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bae9cdb5b5c57cac7183b5876019f4aa5f5eda9f21c9afdc9a02b9c26a3cc6' 
  AND token = 'UnGmn4R9FN/CSwvmMTKKWx5bCjbzdS2jrRDEpVF77kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}