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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd054ec86006e331e203aed5c1df7644f416ebe454cbb179f9209faab7ae7f312' 
  AND token = 'RbK8+rPngW5bKcO8A9c48Ahhw5VBRIRgHfrJt5iCJM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}