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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5dd7da8573bfb400c5052398a2a37bf82a2954034e5de4587a7fcde6974d8f9' 
  AND token = 'KwbVPFTZ7sPZwvOBoUjwufq5fxKi7ZFMEZVY3803EXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}