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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a50c0e6133431bef6c193186ea627fb6fe6d41d3276fc313181af1f093318bf' 
  AND token = 'f3u/e+4ZtEfBIrbTiCBux7LvWuDfTNp6tfn9cnpmH7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}