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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e57c273bc164bb64c34200dd1b0da1a5784a4da566febad27841dd9b170b939' 
  AND token = 'ZOOH0Z9bNBjgYGQ2T2PWKM3W9m8YkHcJ4KhYEjgoLqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}