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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819336d2a4db29345f494bf9c549e6aca74008cf263af55f31303349e59a28df' 
  AND token = 'PAQ5T9hz9xWtSDI8QqHg0V1RhW/DeS6d8tDHqIpd+CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}