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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51fd757ecb7af32e8c6d57dbc32b83346eedce7a399bb739c865d8d01ca06f5' 
  AND token = 'kqQ0KAOp5OmtR3sg6tOjEAqXgJY6IC2UTjNv1wsUifs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}