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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb66c9446e2d9a1790856b678ee3330ca14e9839c151afefa06f1c6cf9f0765' 
  AND token = 'womcOHcjGUkqKfwLx2fz/km45UU7kecAUNfAt1b76ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}