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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53d0f7f3ce98b10066f27ee871fb645ae6fb93eae01f7af8b3eb53b924926cf' 
  AND token = '/+xukjWtOwtgTmYB+TRXg+R5ngOY2mOsiiuiL3VTExQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}