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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78b01f60257e0ce3fdfd7940f3924c6f27565de5cd858695e916c5574478286' 
  AND token = 'lm10c5rwSVmRmImGI2h0Ib99+CKGOm0cB8BcA3YghAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}