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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05618bd57ddc92fa74e01d00deeef884094cc0c74610e92e9f5153a9729cfca' 
  AND token = 'YLk1xcVYHGz3OLrIUnNm+x+0LvrAKAUjOMikTT5tKSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}