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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312b5bd14f8303f1fe15c185535c7efec5055e2df73ea9580c4d8b8b79c06c16' 
  AND token = 'RDRO8G4w5rTjlUi5vf/8A0KN/NLZiqlGF0Wi4IA5GKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}