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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125f41913751da769640aeb3a8202deeb599eabce2ecc7efffb9eb159a65056e' 
  AND token = 'pl/7XUThXeT7VbHR6v7KW3JdIOpA1fUdjx+IrmI9JiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}