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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '523757cc4f08e62eb7f3975fdd9c00991a28df59c50892f840c48077a3bb1a0c' 
  AND token = 'u09GvQUVHAfQOWAv7GUxLho9YYDvEFWYQTe7H7Ye4k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}