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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0d9e6641d5f3d30e25e615a0a61fdb561b73488d1f72c5b3076bb3af729f0a' 
  AND token = 'hJy+7ZLWSHqseI0zYo0SE4kdw9zTIjZrTB3WFCRZUBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}