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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cd5c14e011fe780f6162ffded0635787ea2bd9e6b675cb2738292c45d4ba2c' 
  AND token = 'JbGTYQjAeiwQ4newls2MCv1facbOaMXmzLt9B2vzkqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}