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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8186a68edc79ab02d70173d9d7a3967fec5eaccbd49a9da20d6ba4817839b544' 
  AND token = 'K60Nn6J+GMrN/BpHkWaK3gCxCdJl41yb5jK/JwnIcbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}