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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1878f76488e174b21864aad353bc26f4b3ed02980c30bd368e1d5d4342e153' 
  AND token = '+LQnrLPPrwn2Ooz7N34avpJQ6oZn52wdwHDdjCvYtd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}