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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d8e8525515050e90adc71bf7ee5511e2562f70fa762295da0fce6254c1287c' 
  AND token = 'oTul8+CLoXpetSf2N9BJ+pPq4H3f2LqhDY1J44DOdFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}