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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '559ad03c86aaadea18c809f2d868df31ff3a9be80c4bd8804c1653805dd18772' 
  AND token = 'sMXIBOz4dc5Mt6NaTPT7z9epWoma0MWtMCts9tAkaPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}