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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164fc6c853094059baf249e8fba27e62609c81e26451f1b49e029c8454c48f27' 
  AND token = 'ianu5T0D5RTP1QiPtDQk+3A/HYdmrPBHnCKQIJ7wUHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}