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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '540e9d0c7f5553bf0c0d05b0899c8a8f67ab33f27e2a58b899aad28042c3d905' 
  AND token = 'UsrwPpaJI6dN3C9RffchycADUk/pMtRVvlKo319+lQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}