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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bdc2d5a511014e46dd7408602185d3e9fd23185c009cbc5bb036bb9ab07116e' 
  AND token = 'i3F6H0MafrWPR1E0ok05mCXUu2q+6mXN+gw4Cg7dgQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}