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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70d00ea4e746eb2758adc7fa43bca45c897bacd4bc07d9c9a0565cb6b9a1d7e9' 
  AND token = 'yDJ7GMwX++c1HQAt4sGszfbgA0wt8xfM5YsO2hGYGm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}