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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79e2a96d97ad3d1d049ebec86519bb84ef0f53dded721699a2b932e07a1911bf' 
  AND token = 'TMBfj9ALd2f6vl4TuTOgav1C6FgSDy1G0aMuHIoJXVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}